Friday, October 19, 2012

Hemophilia A (Factor VIII deficiency)..!!



Hemophilia A is a hereditary bleeding disorder caused by a lack of blood clotting factor VIII. Without enough factor VIII, the blood cannot clot properly to stop bleeding.

Causes, incidence, and r
isk factors

Hemophilia A is caused by an inherited X-linked recessive trait, with the defective gene located on the X chromosome. Females have two copies of the X chromosome, so if the factor VIII gene on one chromosome doesn't work, the gene on the other chromosome can do the job of making enough factor VIII. Males, however, have only one X chromosome, so if the factor VIII gene on that chromosome is defective, they will have hemophilia A. Thus, most people with hemophilia A are male.

If a woman has a defective factor VIII gene, she is considered a carrier. This means the defective gene can be passed down to her children. In a woman who carries the defective gene, any of her male children will have a 50% chance of having hemophilia A, while any of her female children will have a 50% chance of being a carrier. All female children of men with hemophilia carry the defective gene. Genetic testing is available for concerned parents.

Risk factors for hemophilia A include:

Family history of bleeding

Being male

Rarely, adults can develop a bleeding disorder similar to hemophilia A. This may happen after giving birth (postpartum), in people with certain autoimmune diseases such as rheumatoid arthritis, in people with certain types of cancer (most commonly lymphomas and leukemias), and also for unknown reasons (called "idiopathic"). Although these situations are rare, they can be associated with serious, even life-threatening bleeding.

1 comment:

  1. WOW ALL THANKS TO DR WILLIAMS I HAVE NEVER BELIEVE IN HERBAL REMEDIES.
    I have been a patient of hemophilia for more then 26 years . I had tried a lot of anti viral med prescribed to me by doctors over the years but I could not see any improvements in my symptoms. One day when going through the internet , i got to know about this great Herbal Dr who uses his herbal remedies in curing people from hemophilia,quickly i contacted him and he prepared a herbal medication for me which i received and used as instructed. After few weeks the improvement were very visible. the pain and tightness in the joints stopped and the sores started to heal. I would recommend this to all my friends,families,around the globe suffering from hemophilia.you can contact him through his email on drwilliams098675@gmail.com.for advice and for his product THANKS TO YOU ONCE AGAIN DR WILLIAMS

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